Understanding the nature and role of endothelium-derived hyperpolarizing factor appears to be crucial in the quest for improved treatments for hypertension, diabetes, ischemia-reperfusion and other vascular disorders. EDHF 2000 comprises the proceedings of the Third International Symposium on endothelium-dependent hyperpolarizations. The first two meetings established a role for EDHF and other chemical factors involved in endothelium-dependent hyperpolarizations. These proceedings focus upon the role of gap junctions in cardiovascular responses and investigate the chemical identity of EDHF. Additional chapters on Physiology, Hormonal Modulation and Pathological Changes are also included. EDHF 2000 will be of interest not only to physiologists and pharmacologists puzzled by the complexity of the interactions between the endothelium and underlying vascular smooth muscle cells, but also clinical researchers and physicians treating patients with cardiovascular diseases.

Science isn't exactly Maeve's favorite subject, but she's still excited to be going to the Sally Ride Science Festival at MIT with her hunky tutor, Matt. Sure, the BSG and her annoyingly brilliant younger brother are going as well, but it's still almost kind of a date, isn't it? The festival gives the BSG a super idea -- an environmental science fair at Abigail Adams Junior High. But plans for a bubble gum factory nearby put Avery and Katani on opposite sides of an environmental issue -- and Avery finds herself in a bubble gum war with the Queens of Mean!